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Antidepressant Update
 
The antidepressant sertraline may reduce the risk of recurrent depression and increase the period of time between episodes of depression in people with diabetes, according to a study supported by grants from the National Institutes of Health and Pfizer, Inc. Earlier studies have shown that about 15 percent of people with diabetes who suffer from recurrent depression do not respond to antidepression treatment. Patrick J. Lustman, M.D., of the Washington University School of Medicine in St. Louis, followed 152 people with diabetes who recovered from depression while taking sertraline. He tracked them for up to one year, or until their depression set in again–at which time they were put back on the drug. Participants taking sertraline were significantly less likely to have a recurrence of depression. After one year, 65.8 percent of those taking sertraline remained depression free, while 47.9 percent of those taking a placebo were without depression.

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